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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e49c90220f1f69a7475213a52e219ce61b3036dfd1cb400a8ed9d88757643fa' 
  AND token = '6amGHaXmpxd1Ql8EINGGsTxzB/5HbuDuuS8mxGsOcXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}