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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c402afb8b458f2c2f5b0b8562e5944da98e574d723cc9a339ca486f05d5b3d98' 
  AND token = 'PG06FRGlJyD9+0Qpsd7nEQ7IsR0qG9O1OiYe2HEtf7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}