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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b778bf4803d6e0fec9bac08b5a5f02cdffbe908ce4894165896992a8627522ab' 
  AND token = 'nImDE3HCmWQ73xa+sZrHEnk3kugXD7vpibMGolqvpiw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}