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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4939b89601164c39c8b2fe8c6fdcad5346e87281f62ce234a93bfa07c4b48170' 
  AND token = 'cWtmFI+KJrVJ4wLzLAuNT4wF79Xyc8Xm3fphEtWnZcU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}