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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b43c21a61f6f4a4e03a3902146a87ecd9e9eac02d3b4397fb02731b18dbbad9d' 
  AND token = 'T4kPmcy9tNiz7n5fCsB7HnXjhjX0Z8YCaxUYA0hmkWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}