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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ddf2eaff048492522591b185cd460995eb98bf0390103d2096a7f23c63f0f11' 
  AND token = '/A51U9b2aIJthEgkV/QMe+GT/Fl4TspOol/DVsz7MSg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}