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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1504abbfe5c1e4f33d2d4658304cb21ac4154f18021ce41557183a86a3b2b33' 
  AND token = 'aAY/WdiQ4rcnc/YAVmB9Ru/pHhm6pw1CVTj1ieI/Uzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}