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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f85c49eb5511989adda9c75fc8f97511d38400b2276884eb412e957f809de5c4' 
  AND token = 'm49EJj6uJBLSRsOPh2LELQDqWxze3Bfm+wcNgnShLpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}