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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6142030d08dd38c4f464fa718a9c3f0db5d1c523379971a1b3c1149aa1bfe8e' 
  AND token = 'GAt9olwpLNOsRaHrzQi9869j/3uSoBpMMubiiR/53BQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}