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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43a101540772a863f005732b92fd4b4e118a7ef524a5ab56ad995c50527d1c34' 
  AND token = 'uAkB/9KcPo7yLkntJbxcShmsc4Y8ztDm6NcyBTF7mC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}