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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e5c3c1fc1b1d86ed401d920d91b5d560795f609c09931c51be4f5c6afce1cfe' 
  AND token = 'bxBRztxZh+X9HJdI20vOW3gll3NwLxj4cmGpjaUXtwc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}