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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72cbbebeccdea256d7cbc424443a726de0ff6a44ddfb1c0d00a9f720c6c4e0a1' 
  AND token = '1sdh5Tk7O8TQkHRHDRqP4PuG0lloXIFwlEaPAmIkmnw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}