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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e00909650187304f6fc05b9fd3b639df2dabdea41a93852cf05fa0fca2a8e2cf' 
  AND token = 'TLheUDPSIj2kaQAbOL96EqbobtkKq48A76ai23kRQug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}