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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9853d565f0e1bb6f639b3d991d14c4e5b0468e86f3c1933ca8256bc6811f3a11' 
  AND token = 'zDEzRNvm0XPKsHRr+aKY1Py58cgI5v5fX0mrO3q0Pi4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}