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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3a64dfca4e60b9d7fba7c822903d21e8840731dc3055485ffd0518857d81b2f' 
  AND token = 'AzqXPvQNNTcyg/hVMA2V7AqCT8tM6RdRYHteQhka+aI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}