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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4497f3f81cc311e0100b3286450129754abe3413f9119e5f85acbefb5a700f40' 
  AND token = 'FhJ5ePVvIS3wY8IRJtW2kJO/eJZiR+sQ60u1Gd5kie4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}