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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '420a35293f9acd86704d9c46005d0758192ee3cb5ae5645f08a6988a2bfb0f4a' 
  AND token = 'kZnNeSgF/ocC9+g3y2y1CRRBVoQ86S43tiQJ7oLCc58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}