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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '02100e04a8dc279244142f60b581ae21789d588395ff64cae93a125b197d68d9' 
  AND token = 'Dt2AKFlIOI/pMzKkL/JI47Rd/1p5vA310WqxXwzaHKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}