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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '755bcbc65024a21c63c0fbf69ff9ecc04934e7399f8dd3d98013dbaea9fd4d80' 
  AND token = 'vNagKWAVoFH9CAkdr/uGE+8NPELrvc6FIULX6/vOz3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}