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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23b5c433e0d2bb42910a1d87ea2ef7758af64e8ec0aa97fe9b75caef543ea1c1' 
  AND token = 'UvAOoRQ3fILYkNwo5N55c/ZmRZAlqy3hWmTCXligpy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}