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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7488fe4c37b22b1e5e987c09db11d0a0f766a2727ddc7f0e506e3c94f477d17c' 
  AND token = 'XAVEJDpnmTkNDj+Bt7a4ARl8QTY/FYb77G/n3XjDVlA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}