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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec6670cb40553125e8f25d911d577f4311ea61891b19d5be9277938592084167' 
  AND token = 'a9mSh6hs5rDJJbke3lMO0rO2IjbtzZH6hVLT9aBy2UY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}