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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5382b8f8e9aac601f4edf2c2c196d2a0ef25f4f43cc69372279b3fd1c4fcb00b' 
  AND token = 'nXunLaIOtyy6UibSZllPj/ZNSU1LgjD/61cTRi7w7Uo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}