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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b42e0ecda7073c386d7640697713b121bba3a50b6069a5931cc9faf232420d1d' 
  AND token = 'Dtie1avRX9qHzL5uW98GsjRe2VDLv2BQxXh/EvJFzE4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}