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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '569ecc1260ee2d572af3a785f1e7dba4ce32dce2ef6a0499edceb386421586e2' 
  AND token = 'Dq8BhmWVYgZ7+2nCuN+r5y42dk1sdWAXAB5GEHi5sN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}