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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1c46a23e2836fefbfd3675d1a32a31eacafe1b1b44eeda17fbb42d51a02ac44' 
  AND token = 'FIytxuKMespYWIh5ApxM/J0E3RlcN2YZWi4ImRjJ8Uc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}