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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '527ec40feca66b734594e560eb1a8113445d606ed2e7730f7621e4e8b2f56b2a' 
  AND token = 'd+zSILiV9F+qFfV6DcpEc8W/+/8UXNpGjUIW5yb+TwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}