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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e849291770b457a2bbc774728540dc805e89eefd49a3d0ffae705a3a19b2ac47' 
  AND token = 'qVOS5WHBCqTPvfBx6iJcWf52SWnQ7lHCTI7unzT1/Po=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}