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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7db47c060bedcc39fc579f49bfd42dddd1228a12effce0e95acf1c664b9f019' 
  AND token = 'F0UzAMR7CHL7MrbWD2NMru+A23o29kdqYmX7QkiU7E4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}