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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53ab39b4bd6845484e49d28d4f8a15e81cbd026efb91690bc18270cd4cc56b90' 
  AND token = 'IbAHtWNAgNC7bqPp3ISvEZSrN4Zm3Y+sahND+zxkmUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}