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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6af99d21a55eef7d09f7b0ccd51ab77f9df5d249a270a2fef055edb7d04b50b1' 
  AND token = 'zMBglQITk9n+MFc3wtn806q3CSTjztqqVupopHk7J38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}