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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1555ad0baf818f65f9f2b76bf91085b879a8a8cd6d016e31da72384c3abb6b4a' 
  AND token = 'jbUdHH0esadC5BAUh2QiQ+yL9Wjeu/NEmzTqL4BsLLI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}