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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '297f62a4ae30fe713df04f79a2f036ce02cc3ac34d5b55a68f48f08c290755c8' 
  AND token = 'DwYuXjtIjMBvJRXRjAfkAEJxuY5GFfDQkQCskW4Z6Tw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}