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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca68e57980c2d05281ffb05b39e2d36c5a4435f23debb5347fa413eadaea68f7' 
  AND token = 'WYw/e7wtwcyWJ7qQ06hlKMhrl4PfNNJ99sy3o1uZx0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}