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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f124d5646120bc4d2ce52e914deee0322d0154676f044111cd319bf51c1d7ef5' 
  AND token = '52DUdBQRaVFig2PTp3YAh7+WZkdbpBFUD3eTBb6OQfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}