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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b093aea8e15643925f081476da1d48b33350716bfda44580e7214d46e77b1037' 
  AND token = 'GMx4T6z7kiSD+CMNAP8aNKnnZcBUqJ+qmWLPLAAFLtc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}