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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75486fd46f909d10510405b3e0e1d70c56671b87e461c702b28b6cb7cb6d14e5' 
  AND token = 'KNOXQceuZz6ULLeYf2Oz32v28W+qrCB4CsBO3pHsNWY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}