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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c8b2b69b9f92326d697fc6f6730fe7eb29f791d45b019b60104cfb939efd2c0' 
  AND token = 'me14Xg2rsUMJSNNx7Oplkp3UumYR8DiXHwGPRYgPDh0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}