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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70ef989d8f222ce4b3eada74881cca933df0c91cf78f488300e7490577b4e476' 
  AND token = 'e/w8GDon+xOKVOdPpSkuWFkWhwcSBdzRDrzFaMwprUk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}