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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee1ccd6acc7ee231f70f461eab13007b47462662820c5caa1f65aa5afc7a265d' 
  AND token = 'f+98UJ2VX5LLgvJJypS+vjW4VOp4V2tN7pO3qqTJwus=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}