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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f388eb26f469bfb14c4c76f6f8c1105c5823aa0a84e5cedc22e6433a3c069e46' 
  AND token = 'Qp5HZ5RQ7uw5sG79GG2Eb9FaDZul5cm9tujYODdwpXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}