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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb1a620e4dce283480f3d4351f0d9265ac4f7ac73918c34482a4e03a9b4e7b01' 
  AND token = 'HCMoeoAy0RekKdq5vpkF0bLSdg3yDaN+kRsCpqbVTYQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}