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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d8c0ef9f0e233a4ffabcb0297766a793506be5218ee9dce3f0dc32ad047b7aa' 
  AND token = 'aeGFnb1eiDe8J6VpyrMiKA7rPNX5IcAdHyjP6hGEPrI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}