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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9bf0a6072ef3921790ee59b7a5e296a50b06b9298a9b415d32065a8b6815495' 
  AND token = 'aFBHSRVEbAw4PMmVnF5g/zYc6HNt0j93v47+PVUV4B8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}