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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bdde0a36e39f68ef235f7468583e459891a158dea7cdd9225b7c2107e2c73396' 
  AND token = '5LcMSdBa7sFC0toBMdty1bXjPUDG1fBChmpgRhIHnc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}