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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d1d102be82acd8bf536a58dc155364d9ab67490ecd3685a0ee38c1b5a1ec394' 
  AND token = 'PdzbLzZ5l2qifUzu2iRbkb0pjVFMRZocEabCde3GUvo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}