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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5ce225e4cc5ad563c23f06656feba8e3e30445e154259b8c947ee2b9333f7bb' 
  AND token = 'V0ajQZROaOMLLwPInN+pysvBFG9nOrxzQD4j+dbqcTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}