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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b956b280af57aea4a4a8685a83542a4f2b54a147c9c4ffed518456428d1e932' 
  AND token = '1ouO7nsWyeZxDcz/yYUtuv8Gb6YDlYxF9MnQkEFCJbw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}