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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd345119787eaa68797522695591df4a4e4c6c2e604b0d4aa4c08b16f21a3f46e' 
  AND token = '/r1uSPX9AmJzk4yuGDUglaWVtnWT2r04cvO0UxTAtg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}