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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7621501893cd9fd550f0f3d8525c3390055837d9681d825761bf3b8c5afd17aa' 
  AND token = 'AD1UO2tv0PI9PeB5ll2OU12vi/Oze/s0qyyA2LXR3QQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}